Measurement Techniques

Splashlake supports data across a variety of measurement techniques, enabling customers from multiple industries to view, process and store scientific data across all their workflows. Our repeatable patterns approach enables us to scale connections easily, delivering information to the scientist in the context they need it in order to advance research or support decisions.

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Balances

Splashlake supports data from analytical and precision balances commonly used for weighing samples, reagents, and formulations. Typical manufacturers include Kern & Sohn, U.S. Solid, METTLER TOLEDO and Sartorius, with software such as LabX frequently used for balance data management. Splashlake captures both results and rich metadata (user, method, tolerances, timestamps), presenting trends, audit trails, and outlier detection to help scientists verify accuracy, ensure compliance, and quickly identify deviations that could impact downstream experiments. Splashlake enables scientists to send weights from balances directly into LIMS/ELN/SAP or CDS sequences, eliminating errors and streamlining sample preparation.

Biolayer Interferometry is widely used for label-free analysis of biomolecular interactions, such as affinity and kinetics. Instruments from providers like Sartorius (FortéBio Octet systems) generate complex kinetic datasets. Splashlake enables visualization of binding curves, comparison across runs or conditions, and correlation with upstream and downstream data, helping scientists assess assay quality and make informed decisions on candidate selection and experimental progression.

Bioreactors are central to cell culture and bioprocess development, producing continuous streams of process data such as pH, dissolved oxygen, temperature, and agitation. Splashlake connects to solutions like Sartorius BioPAT® MFCS/win to aggregate time-series process data, visualize trends and setpoint deviations, and link process conditions to outcomes, supporting process optimization and scale-up decisions.

Blood and clinical chemistry analyzers from manufacturers such as Abbott Alinity generate high-throughput measurement data. Splashlake structures these results for clear visualization and comparison across samples or time points, enabling scientists to rapidly interpret trends, validate methods, and relate results to broader experimental or clinical datasets.

Capillary Electrophoresis systems (Agilent 7100 and SCIEX PA800 Plus), controlled using software such as Agilent Chemstation, OpenLab CDS 2, Waters Empower and 32 Karat provide highly versatile separation across a variety of applications. Key parameters such as migration time, peak area, peak height, and resolution are used to identify and quantify analytes. When combined with robust metadata in Splashlake, CE data can support deeper scientific insight and decision-making.

Cell culture incubators such as the Eppendorf CellXpert® C170i continuously monitor environmental parameters such as temperature, CO₂, and humidity. Splashlake captures and visualizes these conditions over time, allowing scientists to confirm environmental stability, investigate anomalies, and correlate culture conditions with experimental outcomes.

Centrifuges from manufacturers such as Eppendorf, Beckman Coulter, and Thermo Fisher are critical for sample preparation. While traditionally generating limited digital data, modern systems can provide run parameters and logs. Splashlake contextualizes these parameters alongside experimental results, improving traceability and reproducibility of sample preparation steps.

Laboratory ovens from vendors such as Memmert and Binder, often managed with software like AtmoCONTROL, generate temperature and process logs. Splashlake captures and visualizes these time-series parameters to support traceability, method verification, and confidence in sample preparation workflows.

Conductivity meters from providers such as METTLER TOLEDO and WTW (Xylem Analytics) are commonly used to assess solution purity and concentration. Splashlake presents conductivity values with associated calibration and method metadata, supporting quick verification of solution quality and informed decisions during formulation or process development.

Digital PCR techniques, including droplet digital PCR, are widely used for absolute quantification of nucleic acids. Systems from manufacturers such as Bio-Rad generate large datasets related to partitioning, counts, and concentration. Splashlake enables intuitive visualization of results, comparison across experiments, and linkage to sample and method metadata, helping scientists confidently interpret low-level or critical measurements.

Density measurements are commonly performed using instruments from METTLER TOLEDO, often supported by software such as Aquisys 3. Splashlake captures density results and contextual metadata, displaying trends and correlations with formulation or process parameters to support quality control and formulation optimization.

Flow cytometry instruments from vendors such as Sartorius produce high-dimensional datasets describing cell populations. Splashlake structures and visualizes these results, enabling comparison across samples and experiments and supporting data-driven decisions in cell characterization and assay development.

FPLC systems, such as Cytiva’s ÄKTA platforms using UNICORN software, generate chromatograms and fraction data critical for protein purification. Splashlake enables clear visualization of chromatographic profiles, comparison across runs, and linkage to fraction analysis results, helping scientists optimize purification strategies and assess product quality.

FTIR spectroscopy instruments from manufacturers like Bruker and Perkin Elmer produce spectral data used for material identification and characterization. Splashlake connect with software such as Opus to support visualization of spectra, comparison across samples and trend analysis, enabling scientists to quickly interpret results and confirm material properties.

Gas Chromatography is widely used for separation and analysis of volatile compounds in chemistry, pharmaceuticals, and environmental science. Instruments from manufacturers such as Agilent, Bruker, Shimadzu and Thermo Fisher Scientific often integrate with Chromatography Data Systems such as OpenLab, LabSolutions or Chromeleon. Splashlake visualizes chromatograms, peak integrations, and method parameters, allowing scientists to compare runs, assess method performance, and make confident decisions on compound identity, purity, and process consistency.

HPLC is a cornerstone analytical technique for separation and quantification of non-volatile compounds. Systems from vendors such as Agilent, Waters, and Shimadzu generate rich chromatographic datasets. Splashlake presents chromatograms, peak metrics, and metadata in a consistent, comparable format, enabling scientists to evaluate method robustness, track trends across batches, and link results to upstream preparation and downstream analysis.

Ion Chromatography is commonly used for the analysis of ionic species in pharmaceuticals, food, and environmental samples. Providers such as Metrohm and Thermo Fisher Scientific offer dedicated IC platforms. Splashlake enables clear visualization of ion chromatograms and quantitative results, supporting rapid interpretation, method comparison, and informed decisions on sample quality and compliance.

Mass spectrometry techniques generate high-resolution data for molecular identification and quantification. Instruments from manufacturers such as Agilent, Bruker, Sciex, Thermo Fisher Scientific, and Waters often integrate with vendor-specific software. Splashlake structures mass spectral data and associated metadata, enabling comparison across samples and experiments, supporting confident identification, and helping scientists correlate mass data with chromatographic or preparative workflows.

Microscopy techniques generate image-based data critical for understanding structure, morphology, and spatial distribution. Systems from vendors such as Zeiss, Leica, Kern & Sohn and Olympus produce large volumes of image data. Splashlake provides a framework for organizing, contextualizing, and visualizing microscopy outputs alongside experimental metadata, helping scientists draw meaningful conclusions and plan follow-on experiments.

Moisture analyzers are widely used for quality control and formulation assessment, with manufacturers such as METTLER TOLEDO providing integrated solutions. Splashlake captures moisture results with calibration and method context, enabling trend analysis and rapid assessment of material stability and consistency.

MRMS techniques, such as those generated by Bruker solariX systems, provide ultra-high-resolution mass data. Splashlake supports the organization and visualization of these complex datasets, allowing scientists to explore compositional detail, compare samples, and derive insights that guide structural characterization and discovery.

NMR spectroscopy is essential for structural elucidation and compound verification. Instruments from manufacturers such as Bruker commonly use software like TopSpin. Splashlake enables visualization and comparison of spectra, linking results to sample and experiment context so scientists can efficiently confirm structures and decide on next experimental steps.

Particle sizing instruments, such as Malvern Panalytical’s Mastersizer systems, generate distribution data critical for formulation and materials science. Splashlake presents particle size distributions and trends in a clear, comparable format, enabling scientists to evaluate consistency, optimize processes, and assess product performance.

pH meters from manufacturers such as METTLER TOLEDO frequently integrate with software like LabX. Splashlake visualizes pH values alongside calibration data and experimental context, supporting rapid verification of solution conditions and informed decision-making during formulation and process development.

Electronic and manual pipettes from vendors such as Sartorius, Eppendorf, and Gilson play a critical role in sample preparation. Where digital data is available, Splashlake contextualizes pipetting parameters and usage logs alongside experimental results, improving traceability and reproducibility. Volumes dispensed can be sent directly to LIMS/ELN/SAP or CDS sequences to calculate dilution factors to streamline sample preparation.

Plate readers are widely used for absorbance, fluorescence, and luminescence assays. Systems from vendors such as Agilent and Byonoy use BioTek Gen5 software or Absorbance 96 App. Splashlake structures assay results for easy comparison across plates and experiments, enabling rapid assessment of assay performance and biological response.

Polarimeters from manufacturers such as SCHMIDT + HAENSCH, often using Aquisys 3 software, are used to measure optical activity. Splashlake presents polarimetric data with method and sample context, supporting quality control and compound characterization decisions.

qPCR systems, such as those from Thermo Fisher Scientific using QuantStudio software, generate amplification and quantification data critical for gene expression analysis. Splashlake enables visualization of amplification curves and comparative results, helping scientists assess data quality and confidently interpret biological significance.

Raman spectroscopy instruments from manufacturers such as Bruker and Metrohm generate spectral fingerprints for material identification. Splashlake supports comparison and trend analysis of Raman spectra, enabling rapid confirmation of identity and assessment of variability.

Refractometers from vendors such as SCHMIDT + HAENSCH measure refractive index for concentration and purity assessment. Splashlake visualizes refractive index data in context, supporting quick quality checks and formulation decisions.

Rheometers from manufacturers such as TA Instruments, Chemspeed and Anton Paar generate data describing material flow and deformation. With software like RheoCompass or TRIOS, Splashlake presents rheological profiles and trends, enabling scientists to understand material behavior and guide formulation or processing strategies.

SMLS techniques are used to assess stability and particle interactions in dispersions. Splashlake works alongside systems such as the Microtrac TURBISCAN LAB to organize and visualize scattering data over time, helping scientists evaluate formulation stability and make informed optimization decisions.

Temperature measurements are fundamental across laboratory workflows. Splashlake captures temperature data from a range of sources, presenting time-series visualizations that help scientists confirm environmental control, highlight anomalies and investigate deviations.

Automated titrators from manufacturers such as Metrohm (using tiamo and OMNIS software) and METTLER TOLEDO (using LabX software) generate detailed titration curves and results. Splashlake enables visualization and comparison of titration data, supporting accurate endpoint determination and method consistency.

UV/VIS spectrophotometers from vendors such as Agilent, JASCO, Unchained Labs, QIAGEN and Perkin Elmer produce absorbance spectra and quantitative results through software such as UV Winlab and UV Chemstation. Splashlake presents spectra and trends clearly, enabling scientists to rapidly interpret concentration, purity, and reaction progress.

Viscometers from vendors such as Anton Paar generate viscosity data critical for formulation and process control. Splashlake contextualizes viscosity results with method and sample metadata, supporting consistency checks and performance assessment.

Western blot techniques generate image-based and quantitative data for protein detection and expression analysis. Systems such as the Jess Automated Western Blot from Bio-Techne produce complex result sets. Splashlake organizes and visualizes blot data alongside experimental metadata, enabling scientists to compare results, assess reproducibility, and confidently plan next experimental steps.

Supporting Scientific Insight and Decision Making

Across all these measurement techniques, Splashlake focuses on presenting data in ways that align with how scientists work: clear visualizations, contextual metadata, and the ability to compare results across time, instruments, and experiments. By making diverse measurement data accessible and interoperable, Splashlake helps scientists move from raw results to confident decisions faster, and with greater trust in their data.